Access and benefit-sharing is a significant issue in this sector because traditional knowledge (TK) is central to product development, safety and marketing. The vast majority of products stem from European, Traditional Chinese Medicine, Ayurvedic and other medical traditions. Companies also routinely incorporate species new to the market, although demand for access has slowed in recent years due to changes in regulatory frameworks. In may regions, government oversight of the safety, efficacy, identity, purity and quality of products has increased, requiring more expensive and time-consuming research and testing than previously. Demand for access to new species and traditional knowledge persists in this sector, however, but awareness of the Convention on Biological Diversity and the legal and ethical obligations associated with using traditional knowledge, and bringing new species to market, is limited.